Cryogenic Biologic Storage

Ultra-Low Temperature Storage of Biological Materials

In vitro fertilized (IVF) cells, other living cells, tissues, vaccines, biological reagents, and other biologics often require low temperature storage in either ultra-low temperature (ULT) freezers (-20°C to -80°C) or liquid nitrogen Dewars (-90°C to -196°C). These ULT freezers and Dewars must be continuously monitored and scrupulously maintained. Independent temperature monitoring and cryogenic backup systems are essential to insure the viability of these precious biological materials.

Hampshire Controls’ CA5000-C Liquid CO₂ and CA5000-N Liquid Nitrogen Freezer Backup Systems are field-proven, ultra-reliable alarm and liquid cryogenic injection systems with 24- to 48-hour battery backup that maintain ultra-low temperatures within ULT freezers in the event of freezer mechanical failure, coolant loss, or power outage, thereby safeguarding your precious biological materials.

For liquid nitrogen (LN2) Dewar cryogenic cold chain storage, Hampshire Controls’ LD-215 Liquid Nitrogen Level Detector/Alarm is designed to detect low LN2 level (i.e., impending rising temperature) by using a cryo-RTD probe positioned just below the target liquid/gas phase boundary. When the probe registers a sudden increase in temperature due to LN2 evaporation, the LD-215 goes into alert condition. The LD-215 and probe (shown in operation below) include audio and visual alarm indicators, an SPDT relay output, a rechargeable battery backup system, and user-programmable alarm, alarm delay, and alarm mute functions.